Why the Arab region must plan for ‘Disease X’ or the next pandemic

Analysis Why the Arab region must plan for ‘Disease X’ or the next pandemic
WHO researchers anticipate the next “Disease X” will be caused by a new virus derived from one of approximately 25 viral families which have already demonstrated the ability to infect humans. (AFP/ File)
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Updated 18 February 2024
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Why the Arab region must plan for ‘Disease X’ or the next pandemic

Why the Arab region must plan for ‘Disease X’ or the next pandemic
  • WHO and health chiefs have called for a pandemic treaty so the world can better prepare for future outbreaks
  • Gulf states fared better than most during COVID-19 pandemic, but experts believe lessons must still be learned

DUBAI: When the COVID-19 pandemic was declared in March 2020, governments worldwide were caught off guard. Having faced no health emergency of this magnitude in generations, states were left scrambling to protect their populations and shield their economies.

Now that life has largely returned to normal following years of social distancing, travel controls and trade disruption, global health experts are calling on governments to prepare for the next pandemic — ominously dubbed “Disease X.”

Such is the sense of foreboding that the mere mention of “Disease X” — x being the algebraic symbol for the unknown — at this year’s World Economic Forum sparked panic on social media as people took the hypothetical warning literally.




Experts voiced concerns about the likelihood of another pandemic in the future. (AFP/File)

Saudi Arabia’s Ministry of Health was forced to issue a statement to allay fears of a new outbreak, clarifying that “Disease X” was merely a placeholder name issued by the World Health Organization to refer to the possibility of a future pandemic.

The ministry also emphasized that cautionary statements from the WHO and scientists were only intended to promote greater global preparedness in the face of new and emerging threats to public health.

“The recurring message year after year is that humans are vulnerable to epidemics due to our coexistence with numerous viruses and germs,” the ministry said.

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Indeed, although health experts were not announcing the emergence of a sinister new disease, they were voicing concerns about the likelihood of another pandemic in the future — one that could be even more deadly than COVID-19 and that the world is still ill-prepared for.

“If and when it occurs, it would have the potential to cause death and devastation,” Dr. Fabrizio Facchini, a consultant pulmonologist at Medcare Hospital Al-Safa in Dubai, told Arab News.

According to Dr. Facchini, microbiologists and epidemiologists are concerned that a new virus could emerge in the future which would have a similar impact to the deadly Spanish flu of 1918-20.




COVID-19 killed around 7 million people and infected 700 million. (AFP/File)

To put that in perspective, the Spanish flu, or “Great Influenza,” killed an estimated 50 million people and infected approximately one-third of the global population.

By comparison, COVID-19 killed around 7 million people and infected 700 million as of January 2023, according to WHO figures. The pandemic was officially declared over in May that year, although the virus continues to travel.

“Defining this potential threat as ‘Disease X’ is intended to prioritize preparations for dealing with a disease that would not have vaccinations or medications in place and could cause a significant epidemic or pandemic in the future,” Dr. Facchini said.

INNUMBERS

50m — Deaths from Spanish flu, which infected 33% of the global population (1918-20).

7m — Deaths linked to COVID-19, which infected 700m people worldwide (as of Jan. 2023).

Source: WHO, CDC

Two years into the pandemic, the WHO attributed approximately 1.4 million deaths in the Middle East and Asia to COVID-19. While some nations in the region fared better than others, experts believe there are still lessons to be learned for future outbreaks.

“Although the UAE did well in COVID-19 pandemic preparedness compared with most other countries, there are still steps they should take to prepare for a ‘Disease X’ or other possible epidemics,” Chandulal Khakhar, a Sharjah-based pharmacist, told Arab News.

Khakhar believes hospital capacity is something authorities must examine, considering the “significant strain” experienced by healthcare facilities during the pandemic. Additionally, critical care should be prioritized in health centers and hospitals.

“To do this, healthcare should begin in communities, and preventive care should be done at home,” he said.




Health experts want to see a more joined-up approach to pandemic preparation and response. (AFP/ File)

As the COVID-19 pandemic progressed, technology increasingly played a larger role in everyday lives and healthcare systems.

“Wearable devices to track health progress and community health programs should be launched,” said Khakhar. “And remote checkups such as telehealth should be improved and enforced.”

The number of COVID-19 deaths associated with countries in the Middle East and North Africa relative to other regions remained low during the pandemic, both in total and per capita terms, according to data from the Brookings Doha Center.

This trend may be influenced these countries’ relatively young populations, as well as the robustness of healthcare systems, particularly in Gulf states.

Initially, research showed the highest number of deaths per million population were in Lebanon and Iraq. However, the Gulf states experienced an uptick by June 2020, coinciding with some of the highest infection rates in the region.

By autumn, the Gulf countries reported some of the lowest fatality figures in the region, while numbers rose notably in Iraq, Jordan, Oman and Tunisia amid a second wave of deaths in the late summer.

Still, cumulative deaths have remained low in the Gulf despite many parts of the region having grappled with a surge in fatalities when subsequent waves of the virus strained healthcare systems.





Governments and stakeholders can leverage the potential of mRNA vaccine technology to expedite the development of new vaccines if and when needed. (AFP/File)

This was especially evident for Jordan, Lebanon, and Tunisia, where the overall number of deaths increased significantly from 2021 onward.

Health experts want to see a more joined-up approach to pandemic preparation and response, in part to make public health outcomes more equitable between wealthy and developing nations.

In a joint statement issued at the WEF, two dozen heads of state called for a comprehensive shift involving all sectors of government and society, forming the basis of a “pandemic treaty.”

Such an approach aims to enhance national, regional and global capacities and resilience in preparation for future pandemics.

FASTFACT

‘Disease X’ is the name given by scientists and the WHO to an unknown pathogen that could emerge in future and cause a serious international epidemic or pandemic.

Because public health and national defense experts are concerned the next pandemic could be even more damaging than COVID-19, Dr. Facchini said it was incumbent on countries to prepare for “whatever biology brings, whether it is from nature, engineering, or a laboratory accident.”

The WHO first introduced the term “Disease X” in 2017 when discussing priority diseases alongside conditions like Crimean-Congo hemorrhagic fever, Ebola, Lassa fever, Zika, and then COVID-19, which is considered the first “Disease X” — of more to come.

These viruses were flagged as international priorities, emphasizing the need for states to increase their research and development into their symptoms, spread, treatment and inoculation.




Millions of people have been vaccinated since the emergence of COVID-19, greatly reducing the severity of symptoms. (AFP/File)

WHO researchers anticipate the next “Disease X” will be caused by a new virus derived from one of approximately 25 viral families which have already demonstrated the ability to infect humans.

“The next pandemic pathogen may not be a coronavirus at all. Experts are looking into a range of bird flu strains due to increased transmission to and among mammals, as well as several recent human cases in various parts of the world,” Dr. Facchini said.

Millions of people have been vaccinated since the emergence of COVID-19, greatly reducing the severity of symptoms and improving survivability. However, immunization against this particular coronavirus does not guarantee protection against new ones.

“Coronaviruses have caused some of the most deadly outbreaks in recent decades,” said Dr. Facchini.

These viruses — commonly transmitted from animal hosts to humans and causing fatal respiratory infections — have been observed at least three times this century.

While populations may not be protected against the next “Disease X,” governments and stakeholders can leverage the potential of mRNA vaccine technology to expedite the development of new vaccines if and when needed.

The WHO has already initiated measures in preparation for future outbreaks, Director-General Tedros Adhanom Ghebreyesus revealed at this year’s WEF.




Experts suggest regular exercise, maintaining a healthy weight and refraining from smoking as helpful to reducing susceptibility to diseases. (AFP/File)

Proactive steps include the establishment of a pandemic fund and creation of a “technology transfer hub” in South Africa, in part to address vaccine inequity between high and low income countries.

Moreover, Ghebreyesus called on countries to sign the WHO’s pandemic treaty, so the world can better prepare for inevitable future outbreaks.

“The pandemic agreement can bring all the experience, all the challenges that we have faced, and all the solutions into one,” he said.

Regarding the ability to address potential outbreaks effectively, Dr. Facchini stressed the importance of early detection, surveillance and monitoring of possible diseases in both animal and human populations.

“Investing in research and development of new vaccines, global cooperation, public awareness, and education can all help to halt the next pandemic,” he said.




Global health experts are calling on governments to prepare for the next pandemic — ominously dubbed “Disease X.” (AFP/ File)

And, while individuals cannot control every aspect of their health, Dr. Facchini said basic steps can be taken to maximize personal well-being.

These include engaging in regular exercise, maintaining a healthy weight and refraining from smoking and other vices which heighten susceptibility to diseases.

“One of the lessons we learnt from the pandemic was that people in less favorable conditions fared worse,” said Dr. Facchini. “Those in worse health bore the burden of hospitalizations.”


Lebanon aid convoy driver injured after Israeli strike

Updated 3 sec ago
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Lebanon aid convoy driver injured after Israeli strike

Lebanon aid convoy driver injured after Israeli strike
  • Minister of Public Works and Transport Ali Hamieh told AFP that the convoy was carrying “humanitarian aid from the Lebanese government
Beirut: An Israeli strike hit an east Lebanon town as an aid convoy drove through it Tuesday, injuring one of its drivers, a governor and the state news agency said.
The governor of Baalbek, Bachir Khodr, on X reported “an Israeli strike very close to an aid convoy as it drove through the town of Ain” on its way to Ras Baalbek.
He posted a picture from the back window of the car he was in, showing a huge column of smoke billowing up into the sky dozens of meters (yards) behind it.
“The driver of the truck driving directly behind us was injured,” he added.
Israeli strikes hit Ain during “the passage of a convoy consisting of three trucks” heading toward the town of Ras Baalbek, said the National News Agency (NNA).
“One of the aid trucks heading to Ras Baalbek was damaged as a result of the blowback of the strike in Ain, which led to the injury of the truck driver.”
Minister of Public Works and Transport Ali Hamieh told AFP that the convoy was carrying “humanitarian aid from the Lebanese government.”
It “was traveling to the area accompanied by the Lebanese Red Cross with agreement from the United Nations,” he said.
The convoy was made up of five trucks, and carried aid from several countries including the United Arab Emirates and Turkiye.
Two had previously unloaded goods in Baalbek, NNA said.
Almost a year of cross-border fire, Israel on September 23 increased its strikes against Lebanese militant group Hezbollah in south and east Lebanon, as well as the capital’s southern suburbs.
The escalation has killed more than 1,300 people, according to an AFP tally of official figures.

‘Extremely valuable’ secret tomb uncovered in Jordan’s Petra

‘Extremely valuable’ secret tomb uncovered in Jordan’s Petra
Updated 12 min 57 sec ago
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‘Extremely valuable’ secret tomb uncovered in Jordan’s Petra

‘Extremely valuable’ secret tomb uncovered in Jordan’s Petra
  • 12 skeletons, hundreds of artifacts recovered as lead archaeologist hails ‘rare’ find
  • Discovery may offer new clues about ancient Arab society

LONDON: Archaeologists have uncovered human remains and hundreds of artifacts in a hidden tomb in Petra, Jordan, The Times reported.

The discovery of the 2,000-year-old underground site could help researchers solve long-running questions over the origins of the ancient city and those who built it.

Located underneath Petra’s Treasury, the tomb contained 12 well-preserved skeletons and hundreds of bronze, iron and ceramic artifacts.

The joint US-Jordanian archaeological team that made the discovery worked underneath the famous edifice, which has been featured in films including “Indiana Jones and the Last Crusade.”

Based on the central location of the tomb within the UNESCO World Heritage Site, it is believed to have been commissioned by inhabitants of prominent social standing.

Hundreds more items are expected to be recovered as excavation continues, according to lead archaeologist Dr. Pearce Paul Creasman, executive director of the American Center of Research.

Petra’s Treasury was named as such because of an early theory that it held the treasure of a pharaoh, but most researchers today believe that it was a tomb built by Nabataean King Aretas IV, who ruled from about 9 B.C. to 40 A.D.

This has been supported by the latest discovery, as archaeologists believe the uncovered tomb predates the Treasury.

Creasman said his team dated the hidden tomb to the first century B.C. using luminescence dating, which tracks the last exposure of mineral grains to sunlight. The archaeologists first discovered the tomb using ground-penetrating radar.

The recovery of its contents is a rare event. Many other tombs have been discovered across Petra over the years but most were empty, having been used multiple times throughout the centuries.

“It is rare to find a tomb with human remains in Petra,” Creasman said. “So, when you do find one, that becomes extremely valuable.”

The first historical record of the Nabataean civilization was in 312 B.C. They had repelled an invasion launched by Antigonus, the former general and successor of Alexander the Great who inherited large parts of the Macedonian Empire.

“They just appear in the historical record and then it goes over a hundred years before we read about them in text again, by which time they have this fully fledged society and Petra is being built in the sense that we know it today,” Creasman said.

Little is known of early Nabataean society, though ancient recordings suggest that the civilization was remarkably egalitarian, as there is little difference between noble and common Nabataean tombs.

The discovery of the Petra tomb may offer new clues about the ancient Arab society, including diet and nutrition, Creasman said.

“This is going to help us learn more about a shared, regional past,” he added. “The Nabateans were a multicultural trading society who only worked because they united as a people. I hope they might be able to teach us something today.”


Israeli army says intercepts two drones approaching from Syria

Israeli army says intercepts two drones approaching from Syria
Updated 5 min 25 sec ago
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Israeli army says intercepts two drones approaching from Syria

Israeli army says intercepts two drones approaching from Syria
  • Israel is fighting a war on two fronts, one on its northern border with Lebanon, the other with Hamas in Gaza, while also facing attacks from Iran-backed militants in Syria, Iraq and Yemen

JERUSALEM: The Israeli military said it intercepted two drones approaching from Syria on Monday, a day after a drone attack by Lebanon’s Hezbollah on a base killed four soldiers.
“A short while ago, two UAVs that approached Israeli territory from Syria were successfully intercepted by the IAF (air force). The UAVs were intercepted before crossing into Israeli territory,” the military said in a statement.
Israel is fighting a war on two fronts, one on its northern border with Lebanon, the other with Hamas in Gaza, while also facing attacks from Iran-backed militants in Syria, Iraq and Yemen.
Hezbollah has historically relied on its ally Syria to transport arms and other equipment from its main backer Iran.
Israeli authorities rarely comment publicly about individual strikes or operations involving Syria, but have repeatedly said they will not allow Iran to expand its sway over the region.
Last week, the Israeli army said its forces killed a Hezbollah figure inside Syria, Adham Jahout, who was described as an intermediary who “relayed information from Syrian regime sources to the Hezbollah.”
Iran and Hezbollah have been among the Syrian government’s most important allies in the country’s more than decade-old civil war.
On October 30, an Israeli air strike hit a road linking Syria and Lebanon as Israel tried to cut off supply routes of Hezbollah, according to a Syrian war monitor.
That strike came less than a week after Israeli jets struck the main Lebanon-Syria border crossing of Masnaa in Lebanon’s eastern Bekaa Valley, cutting off the road to traffic.
A deadly strike blamed on Israel on April 1 against Iran’s diplomatic mission in Damascus levelled the embassy’s consular annex, killing seven Revolutionary Guard members, including two generals.
Nearly two weeks later, Iran launched a wave of missiles and drones at Israel, Tehran’s first-ever direct assault on Israeli territory since the establishment of its Islamic republic in 1979.


Hezbollah targets Israeli naval base after deadly drone strike

Hezbollah targets Israeli naval base after deadly drone strike
Updated 14 October 2024
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Hezbollah targets Israeli naval base after deadly drone strike

Hezbollah targets Israeli naval base after deadly drone strike
  • The group said its fighters launched rockets at a naval base near Haifa

BEIRUT: Hezbollah said it targeted an Israeli naval base on Monday, a day after a drone strike killed four soldiers in the deadliest attack on Israel since the war in Lebanon began.
The group said its fighters launched rockets at a naval base near Haifa in northern Israel, calling it a tribute to its leader, Hassan Nasrallah.
The Israeli military said on Monday it had intercepted another launch aimed at a training camp at Binyamina, also near Haifa, a day after four soldiers were killed and dozens more wounded in a Hezbollah drone strike.
On Monday, Israeli army chief Lt. Gen. Herzi Halevi visited the Golani Brigade’s training camp in Binyamina, and told soldiers: “We are at war, and an attack on a training base on the home front is difficult and the results are painful.”
Israeli volunteer rescue service United Hatzalah said its teams in Binyamina assisted more than 60 people with mild to critical injuries.
Israel and Hezbollah have been at war since Israel intensified its strikes on Lebanon on September 23 and sent ground troops across the border a week later.
Israel has vowed to secure its northern border to allow tens of thousands of people displaced by nearly a year of Hezbollah rocket fire launched. Hezbollah says the rocket fire is in solidarity with its Palestinian ally, Hamas.
The war, which saw an expansion in fighting and air strikes around Lebanon at the weekend, has killed more than 1,300 people, according to an AFP tally of Lebanese health ministry figures.
On Sunday, Hezbollah threatened more attacks if Israel’s continues its offensive in Lebanon, warning Israel what it saw was “nothing compared to what awaits it if it decides to continue its aggression.”
Escalating violence
In Lebanon, Israel has expanded its air strikes mainly on Hezbollah strongholds, while its troops in south Lebanon have engaged in fierce fighting.
Hezbollah said it shelled Israeli troops inside a southern Lebanese village Monday, after saying it targeted soldiers elsewhere along the border.
Lebanon’s official National News Agency reported Sunday that Israeli forces had escalated air strikes on southern Lebanon, pounding border villages.
Lebanon’s health ministry said Israel’s strikes on Saturday killed 51 people, including 16 in Maaysra, a Shiite Muslim village in a Christian-majority area north of Beirut.
In Nabatiyeh, in the south, residents spoke of their shock and grief after its marketplace was hit on Saturday.
“I’m staying here and I will not leave... Nabatiyeh is our mother. It’s heartbreaking to see people’s livelihoods gone,” said Tarek Sadaka, barely holding back tears.
Others have fled the city, with more than one million Lebanese leaving areas that morphed into war zones within weeks.
A UN peacekeeping force deployed in Lebanon since Israel’s 1978 invasion has been thrust onto the front lines of the latest war, with Israel repeatedly calling on it to abandon their positions.
On Sunday, Israeli Prime Minister Benjamin Netanyahu called on them to withdraw for their own safety and said their presence had “the effect of providing Hezbollah terrorists with human shields.”
Five United Nations peacekeepers were injured in a series of incidents last week, with the latest seeing the UN force accuse Israeli troops of breaking through a gate and entering one of their positions.
The Israeli military later said a tank “backed several meters into a UNIFIL post” while “under fire” and attempting to evacuate injured soldiers.
UN chief Antonio Guterres said “attacks” against peacekeepers “may constitute a war crime.”
Three Lebanese soldiers were wounded on Sunday, the country’s army said, when Israeli forces fired on military vehicles in south Lebanon.
War on Gaza
The war in Lebanon erupted nearly a year after Hamas staged the deadliest-ever attack on Israel on October 7, 2023, sparking the conflict in Gaza.
The attack resulted in the deaths of 1,206 people, mostly civilians, according to an AFP tally of official Israeli figures.
The number includes hostages killed in captivity.
The war in Gaza has killed, according to the health ministry in the Hamas-run territory, 42,289 people, the majority civilians. The UN has described the figures as reliable.
Gaza’s civil defense agency said Israeli shelling late Sunday on a school used as a shelter for displaced people had killed 15 people. The Israeli military said it was looking into the reports.
“The Al-Mufti school was bombarded with a large volley of Israeli artillery, resulting in an initial death toll of 15 martyrs, including children, women and entire families, and 50 wounded,” said its spokesman, Mahmud Bassal.
Regional tensions
With the wars in Lebanon and Gaza showing no sign of abating, fears of an all-out regional conflict have seen Iran, which backs Hezbollah and Hamas, engage in diplomatic efforts with allies and other powers.
Israel has vowed to retaliate against Iran’s missile strike of October 1, prompting a pledge from Tehran’s side that it would hit back if it is hit.
Iran has, for decades, financed and trained militant groups in Lebanon, the Palestinian territories and beyond, but it has yet to enter into direct conflict with its arch enemy, Israel.
On Sunday, Iran’s President Masoud Pezeshkian spoke with his French counterpart, Emmanuel Macron, to seek support for a Gaza and Lebanon ceasefire, according to the Iranian presidential website.
According to Macron’s office, the French leader appealed to Iran to support “a general de-escalation” in Lebanon and Gaza.
The Pentagon said it would deploy a high-altitude anti-missile system and its US military crew to Israel to help the ally protect itself from potential Iranian attack.


Second phase of polio vaccination campaign begins in Gaza, WHO says

Second phase of polio vaccination campaign begins in Gaza, WHO says
Updated 14 October 2024
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Second phase of polio vaccination campaign begins in Gaza, WHO says

Second phase of polio vaccination campaign begins in Gaza, WHO says
  • Aid groups carried out a first round of vaccinations last month

GENEVA: The World Health Organization said on X on Monday that the second phase of a polio vaccination campaign had started in central Gaza.
Aid groups carried out a first round of vaccinations last month, after a baby was partially paralyzed by the type 2 polio virus in August, in the first such case in the territory in 25 years.